What is the clinical significance and use of my country's stem cell bank construction?
2020-06-23
In 1968, the world's first clinical application of stem cells: bone marrow transplantation to treat patients, opened the curtain for the clinical application of stem cells. Stem cells thus boarded the stage of medicine and became a bright pearl in the history of medicine!
In recent years, China has also made considerable progress in the field of stem cells and transformation research, and has mastered many key technologies of stem cells. Related stem cell products have entered the stage of clinical trials. Among them, the construction of stem cell bank is the basic link in stem cell transformation and clinical application. Only with a solid foundation can we quickly achieve a mature stem cell treatment model.
The establishment of stem cell banks has become an international mainstream trend, and my country has also made important progress in establishing stem cell banks. In January 2017, the National Development and Reform Commission released the "Thirteenth Five-Year Plan for Biological Industry Development", which made a clear deployment of promoting the development of immune cell and stem cell technology, and proposed to accelerate the construction of a new medical model based on stem cells and regeneration technology, and continue to deepen stem cells. With the clinical application of regeneration technology, support the construction of a number of bio-industry innovation development platforms such as stem cell banks.
Three clinical significances of my country's stem cell bank:
1. Conducive to the protection of my country's genetic resources
Stem cells are a precious biological genetic resource. It can not only treat various refractory diseases, but also be used for anti-aging health care. Its unique tissue repair ability and immune regulation function are favored and focused by scientists. But stem cells need to be protected because of their ethnic differences and genetic inheritance.
On June 10, 2019, the Premier of the State Council promulgated the "Regulations on the Management of Human Genetic Resources of the People's Republic of China". The state supports the rational use of human genetic resources to carry out scientific research, develop biopharmaceutical industry, improve diagnosis and treatment technology, and improve China's biosafety guarantee capabilities. People's health protection level.
2. Help to improve the quality of stem cell preparation
The stem cell bank is conducive to the establishment of a complete set of stem cell preparation standards, quality control and information management, the promotion of global stem cell research exchanges and cooperation, and the formulation of a unified stem cell quality system to provide high-quality seed cell resources for stem cell therapy.
In 2015, the General Office of the National Health and Family Planning Commission and the General Office of the Food and Drug Administration issued the "Guidelines for Stem Cell Preparation Quality Control and Preclinical Research (Trial)" to strengthen the quality management of stem cell preparations and clinical research in China to ensure the safety of stem cell treatment And effectiveness.
3. Conducive to strengthening the standardized management of stem cells
Establishing a stem cell bank is conducive to standardizing the collection, processing, storage, detection, and distribution of stem cells. The clinical application, pathology, treatment, and follow-up of stem cells can be coordinated and managed, which promotes the sustainable development of stem cell clinical applications.
At present, according to the different sources and types of stored stem cells, they are divided into umbilical cord hematopoietic stem cell bank, umbilical cord mesenchymal stem cell bank, placental hematopoietic stem cell bank, placental mesenchymal stem cell bank, etc.; stem cells are divided into embryonic stem cells, adult stem cells and IPS according to types Cells and other, different stem cell classification management is conducive to management and identification.
The use of stem cell bank:
1. Stem cells can be used for pre-clinical research, including basic research of stem cells and animal model research;
2. Stem cells can be used in clinical trials, mainly for the treatment of various diseases;
3. The ultimate goal of stem cells is to achieve clinical application and reduce patient distress and pain.
In summary, the establishment of a stem cell bank can provide a stable source of seeds for stem cell research and clinical application. Under the guidance of the correct national guidelines, stem cell therapy will popularize the public and benefit the people!
